Day 1 - Monday, May 27, 2002
Session 1: 8:30 - 9:00 AM
What is Medical Informatics?
Faculty
James Cimino,
M.D.
Educational Objectives
The class will develop its own definition of Medical Informatics and discuss
the personal qualities and skills needed for success.
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Session 1A: 9:00 - 10:00 AM
HPCC, NII, Current Issues in Medical Informatics
Faculty
Donald A.B. Lindberg,
M.D.
Educational Objectives
This lecture will summarize the federal interagency High Performance Computing
and Communications program accomplishments in non-medical and health related
aspects and will enumerate some past, current, and future research funding
sources.
At the completion of the session, participants will:
-
Understand the "interagency model" and the government-industry-university
approach to the HPCC work.
-
Understand the initial opportunities in biomedical applications of the
NII.
-
Have a beginning set of funding contacts.
Session Outline
-
High Performance Computing and Communications federal program
-
Background and Legislation
-
Objectives and Organization
-
Phase 1
-
Accomplishments - Grand Challenges
-
Progress on Grand Challenge Problems
-
Phase 2
-
National Information Infrastructure
-
National Challenge Applications
-
NLM Role in the NII
-
Intramural Research
-
Extramural Research
-
NII medical testbed
-
Telemedicine
-
Computer-based patient record
-
Public Policy Issues
-
Medical Data Privacy
-
National Security
-
Intellectual Property Rights
-
Traditional Copyright Demands
-
Today's Revolution in Electronic Publishing
-
Federal Research Funding Sources for Medical Informatics
-
NLM Programs
-
Other HHS Programs
-
Other federal agency support
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Session 2: 10:30 AM - 12:00 N
Telemedicine
Faculty
Michal
Ackerman, Ph.D.
Educational Objectives
This lecture will summarize the NLM's historical involvement in telemedicine
and discuss the concept of telemedicine as an information process.
The need for medical data privacy and the role of HIPAA will be discussed.
At the completion of the session, the participant will:
-
Understand telemedicine as an information process
-
Become familiar with HIPAA and the misconceptions associated with its implementation
-
Be familiar with the NLM Telemedicine Program as a demonstration of how
information can influence health outcomes.
Session Outline
-
History
-
Definition
-
Information to support medical decision making
-
Signal processing and imaging
-
Arrangements to practice medicine at a distance
-
Security and privacy of medical records
-
HIPAA
-
NLM's National Telemedicine Initiative
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Session 3: 1:30 PM - 3:00 PM
Healthcare and the Next Generation Internet
Faculty
Michal
Ackerman, Ph.D.
Educational Objectives
This lecture will summarize the concepts of a next generation internet
and discuss the federal interagency Next Generation Internet program as
well as the academic Internet2 Project. The application of NGI technology
to healthcare will be demonstrated through the NLM Next Generation Internet
Program.
At the completion of the session, the participant will:
-
Understand the national need for a high-speed/high-reliability network
and its relevance to healthcare
-
Be familiar with the federal Next Generation Internet Program and the academic
Internet2 Program, and how the two are inter-related.
-
Be familiar with the NLM/NGI Program as a demonstration of the relevance
of NGI technology in healthcare.
Session Outline
-
The National Challenges
-
Current Internet vs. NGI
-
Passive vs active
-
"Quality of Service" (QoS)
-
Priority services
-
Federal Next Generation Internet Program
-
Agencies
-
Goals and metrics
-
Applications areas
-
Academic Internet2 Project
-
Project goals
-
Corporate partners
-
Applications and application areas
-
Middleware
-
Abilene Network
-
NGI and Internet2
-
Joint engineering objectives
-
NLM/NGI Program
-
"Networking Health: Prescriptions for the Internet"
-
Needed NGI services
-
Phase I: Planning (FY-99)
-
Phase II: Implementation (FY-00/02)
-
Phase III: Scaling (FY-03/05)
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Session 4: 3:30 PM - 5:00 PM
Workshop:
Class of 2002 Personal Web Pages
Faculty
David Remsen, MBL staff
Educational Objectives
This hands on laboratory will introduce participants to WYSIWYG HTML editing,
basic digital image editing and compositing, and publishing web pages to
a server.
At the completion of the session, participants will:
-
Have created a personal web page with one or more images, and hyperlinks
using free HTML editor (Netscape Composer)
-
Have a basic understanding of digital image editing software (Photoshop).
-
Have created a class resource that enables participants to know one another
better
Evening Session
Principles
of Web page design
Faculty
David Remsen, MBL staff
Educational Objectives
At the completion of this session, participants will have an understanding
of Hypertext Markup Language (HTML) and its application in the creation
of World Wide Web pages.
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Day 2 - Tuesday, May 28, 2002
Session 1: 8:30 AM - 10:00 AM
Encryption and public policy issues
Faculty
Donald A.B. Lindberg,
M.D.
Educational Objectives
This lecture and discussion will present the theoretical and practical
bases for recommendations concerning medical data privacy, data encryption
technology, and some of the national security considerations.
At the completion of the session, participants will:
-
Know the issues facing the US regarding copyright and database protection
world-wide
-
Know if they support or do not support federal privacy legislation, and
its features
-
Understand the basis for current data encryption methods.
-
Will have tested at least two Security Token Authentication devices.
-
Know if they prefer to operate Challenge Response or Time Synchronous security
devices.
Session Outline
-
Intellectual Property Rights
-
WIPO Treaty proposals
-
Pub Med Plans
-
Encryption
-
Basic concepts
-
DES Public-Private Key
-
Implementation and Devices
a) Data Encryption Technology
-
Private Key Encryption
-
Digital Encryption Standard
-
Kerberos
-
Public-Private Key Encryption
b) System Considerations
-
Length of Cipher Keys
-
Security Token Authentication
c) Devices
-
Challenge - Response
-
Time Synchronous
-
Medical Data Privacy
-
Requirements
-
Legislation
-
Overview
-
Status of Federal Privacy Legislation
-
Contentious Issues
-
Initial Practical Experience with Medical Data Privacy Assurance
Session 2: 10:30 AM - 12:00 N
The Unified Medical Language System; Internet Futures
Faculty
Lawrence
C. Kingsland, III, Ph.D.
Educational Objectives
This lecture has two independent segments. The first segment introduces
the Unified Medical Language System (UMLS) project initiated by the National
Library of Medicine in 1986. The second segment discusses several
aspects of upcoming technologies that are having and will have an impact
on the way we view and use the Internet. At the completion of the
session, participants will:
-
Have received an introduction to the history of the Unified Medical Language
System
-
Be introduced to the content of the UMLS Knowledge Sources: the Metathesaurus,
the Semantic Network and the SPECIALIST lexicon
-
Have viewed a demonstration of the UMLS Knowledge Source Server
-
Have viewed a demonstration of the UMLS Metathesaurus browser application
in the Internet Grateful Med program, including the introduction of related
concepts and co-terms
-
Have received an introduction to technologies that are shaping the further
development of the Internet and the ways we use it.
Session Outline
-
Unified Medical Language System
-
History
-
The UMLS Metathesaurus
-
The UMLS Semantic Network
-
The SPECIALIST lexicon
-
The UMLS Knowledge Source Server
-
The Internet Grateful Med Metathesaurus browser as an example of a UMLS
application, with emphasis on related concepts and co-terms
-
Internet Futures
-
Context
-
Internet Protocol (IP)
-
IPv6
-
Quality of Service (QOS)
-
Optical switching
-
Virtual Private Networks (VPNs)
-
Digital Spread Spectrum
-
Bluetooth
-
Wireless Access Protocol (WAP)
-
Ubiquity (wearable computing)
-
Dynamic content
-
Standards/open source
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Session 3: 1:30 - 3:00 PM
Introduction
to Personal Databases
Faculty
David Remsen
Educational Objectives
This hands on workshop will create sample databases and discuss the implications
of different data models.
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Session 4: 3:30 - 5:00 PM
PubMed and the NLM Gateway
Faculty
Kathi
Canese
Educational Objectives
This lecture and lab session will discuss the National Library of Medicine's
PubMed interface for searching MEDLINE. Searching techniques will
be presented as well as a review of recent enhancements including the new
"Cubby" feature. There will also be a demonstration of NLM's Gateway
system which will provide an interface for searching multiple NLM products.
Students will be provided with hands-on lab time.
Session Outline
-
PubMed Overview
-
Automatic Term Mapping
-
Search Formulation and Retrieval
-
Search Refinement
-
Feature's Bar (Limits, Preview/Index, History and Clipboard)
-
Related Articles
-
LinkOut
-
Cubby
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NLM's Gateway Overview
-
Searching Multiple Databases
-
Using MeSH
-
Define Your Own Display Format
-
Hands on lab time
Evening Session
Principles of Database Design
Faculty
James Cimino,
M.D.
Educational Objectives
This lecture and lab session will introduce basic principles of organization
of data in computerized systems. At the completion of the session, participants
will:
-
Understand the historical evolution of computerized data handling methods
-
Know the relative strengths and weaknesses of hierarchical, relational,
information network, and object-oriented database systems
-
Understand the process of development of a set-theory-based relational
data model, including entity-relationship definitions, principles of fully
normalized relational models, state transitions and data flow diagrams.
-
Understand the design principles involved in the transformation of a flat
file record structure to a normalized relational structure (lab exercise).
Session Outline
-
Database definitions and paradigms
-
What is a Database?
-
Historical Evolution of data management techniques
-
General benefits of Database Management Systems (DBMSs)
-
DBMS types
-
Heirarchical
-
Information Network (linked lists and pointers)
-
Relational
-
Object-oriented
-
XML
-
Principles of Relational database design
-
Representation of real world objects and their attributes
-
Relationships between objects
-
Table notation formalisms
-
Relationships: one-to-one, one-to-many, many-to-many
-
System design and building methods
-
Entity-relationship diagrams
-
State Transition Models
-
Data Flow Diagram
-
Transforming flat files to tables
-
A sample problem in database design
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Day 3 - Wednesday, May 29, 2002
Sessions 1 and 2: 8:30 AM - 12:00
N
Evaluation Methods in Medical Informatics
Faculty
Charles P.
Friedman, Ph.D.
Session Outline
This section of the course examines medical informatics as an empirical
science. As such, the section will focus on formal studies of applications
of information technology in medicine. We refer to these applications
generically as information resources. Studies can be conducted while
information resources are under development as well as after they are in
routine service. Studies typically address questions such as: Is
the resource functioning as anticipated? How can it be improved?
Does it make a difference? Are the differences it makes beneficial?
Within medical informatics, there is increasing interest in evaluation
and empirical studies. From an administrative perspective, as institutions
invest in new technology, it is critical for them to know how these systems
can contribute to health care, education, and research so they can set
develop plans and set priorities. From a more academic perspective,
research projects in informatics, including doctoral dissertations and
masters theses, now often include an evaluation or empirical study component.
Much of the funded research in informatics is required to have such a component.
This day-long session on evaluation will provide participants with an
understanding of the range of evaluation methods that are used in informatics
and will address how studies are designed as well as how data for these
studies are collected, analyzed, and reported. We will address during
the day many of the challenges that make evaluation difficult, emphasizing
those challenges that are particular to medical informatics, and we will
discuss methods that have been developed for addressing many of these challenges.
Educational Objectives:
At the completion of the session, participants will be able to:
-
Describe the purposes of evaluation in medical informatics.
-
List several factors that can make it difficult to do evaluation in medical
informatics effectively, as well as strategies that can be employed to
address these difficulties.
-
Distinguish objectivist (quantitative) and subjectivist (qualitative) approaches,
describe the assumptions that underlie them, and explain why both methods
are used.
-
Identify the major steps in the process of conducting objectivist and subjectivist
studies.
-
Identify the individuals or groups comprising the “audience” for an evaluation
study.
-
Describe how the methods and purposes of a study can be matched the level
of maturity of an information resource.
-
Frame many of the recurring difficulties of evaluation in medical informatics
as problems of measurement.
-
Distinguish between measurement errors that are issues of reliability from
those that are issues of validity. Distinguish between different
types of validity.
-
Explain how “measurement studies” can be conducted to identify the sources
of error in any measurement process, and to estimate the magnitude of these
errors.
-
Explain what is meant by a “gold standard” in the framework of a measurement
study.
Identify measurement methods and features of measurement instruments
that can be employed to reduce measurement errors.
-
Identify some specific evaluation questions or issues that lend themselves
particularly well to subjectivist approaches.
-
Explain how the questions and key issues of a study arise through the process
of immersion.
-
Describe the major data collection strategies in subjectivist research,
how these are used in a complementary way within a study, and how the data
generated by each are analyzed.
-
Explain the steps a researcher can take to ensure the veracity of the findings
of a subjectivist study.
-
Describe some of the barriers to combining objectivist and subjectivist
methods within a single study.
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Session 3 - 1:30 - 3:00 PM
Data Capture and Speech Recognition
Faculty
Justin Starren,
M.D., Ph.D.
Goals:
1. Understand the major sources of Biomedical Informatics Data
2. Be able to list 3 approaches to data acquisition
3. Be able to describe two types of ASR systems
4. Understand the role of NLP in structuring information
Outline:
1. Sources of Data
2. Signal Acquisition
3. Image Acquisition
4. Collecting Data from People
5. Speech Recognition
6. What is NLP?
7. Medical Sublanguage
8. NLP Challenges
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Session 4 - 3:30 - 5:00 PM
Human Computer Interaction
Faculty
Justin Starren,
M.D., Ph.D.
Educational Objectives
Goals:
1. Be able to describe importance of formal HCI design.
2. Be able to identify major trends and themes in the field
3. Be able to list and apply heuristic interface principles
4. Understand importance and fundamentals of accessible design.
Outline:
1. What is HCI?
2. Psychology of User Interfaces
3. Psychology of Perception
4. Basic HCI Principles
5. Information Design
6. Web Usability
7. Accessibility
8. Evaluating User Interfaces
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MBL Clambake (no evening workshop)
Day 4- Thursday, May 30, 2002
Sessions 1 and 2: 8:30 AM - 12:00 N
Principles of Controlled Terminology
Faculty
James J. Cimino,
M.D.
Educational Objectives
This session examines medical data, where they come from, how they are
represented , and how they are used. In order for a computer to manipulate
data symbolically, the data must be represented in a way that the computer
can "understand"; this is generally accomplished through the use of controlled
terminlogies. The objectives for these sessions are:
-
Define medical terminologies and their attributes
-
Review the state of the art
-
Examine advanced uses of medical data through the use of advanced terminologies
Session Outline
-
Examination of typical medical data
-
Uses of medical data
-
Terminology characteristics
-
Terminology desiderata
-
Survey of what's available
-
ICD9-CM and ICD-10
-
DRGs
-
NDC Codes
-
SNOMED
-
Read
-
Nursing terminologies
-
MEDCIN
-
LOINC
-
MeSH
-
UMLS
-
The Medical Entities Dictionary
-
Case studies of advanced uses of data
-
Summary reporting
-
HCFA requirements
-
Clinical research
-
Expert systems
-
Automated decision support
-
Linking to on-line information sources
-
Learning more
Sessions 3 and 4: 1:30 - 5:00 PM
Decision-Analytic Methods for Evidence-based
Practice
Faculty
Suzanne
Bakken, RN, DNSc
Educational Objectives
At the conclusion of the workshop, the learner will be able to do the
following:
-
Define evidence-based practice.
-
Describe the informatics foundation for evidence-based practice.
-
Identify the components of expected value decision making.
-
Construct and solve a decision tree using a decision analysis software
package.
Outline
-
Definitions of Evidence-based Practice
-
Information Foundation for Evidence-based Practice
-
Introduction to Probabalistic Reasoning
-
Expected Value Decision Making
-
Building and solving a decision tree using DATA
-
Web-based utility assessment
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Evening Workshop: 7:00 - 9:00 PM
Building
Web Intefaces to Databases
Faculty
David Remsen, MBL staff
Educational Objectives
This workshop will give participants hands-on experience in serving databases
to the web. In this session they will learn the different necessary
components of a database web server. They will create their own interface
to a database and learn how to conditionally format the results in HTML.
They will get an understanding how HTML form elements translate to database
calls, how an HTML form translates to a database query, and how a query
is processed and the results are returned.
Session Outline
-
Present an overview of a generic database web serving system. This overview
will consist of identifying and defining the function of the the different
elements that compose a database server.
-
A brief introduction to a few of the different database solutions to show
how different vendors address the model described in 1.
-
Create an interactive web database using Filemaker Pro 4.0 with a sample
database which will address the following: Querying the database
using FORM and embedded URLS
-
Editing a Record via the web
-
Adding/Deleting Records
-
Processing results with format files.
-
Understanding how HTML and database meta tags can interact by:
-
a. Listing multiple records
-
b. Formatting a single record
-
c. Using conditionals to selectively format records
-
d. Using color and graphics with numeric content
Creating embedded links to Entrez, PubMed, others
Day 5 - Friday, May 31, 2002
Session 1: 8:30 - 10:00 AM
Digital Library Research
Faculty
Alexa T. McCray,
Ph.D
Educational Objectives
This lecture presents the basic principles and practices involved in designing
and implementing a digital library, as well as the research issues that
need to be addressed. Two case studies are introduced, and participants
are given an opportunity to do a short exercise
-
Understand the basic principles that underlie the design, implementation,
and maintenance of a successful digital library.
-
Have an understanding of digital library research issues.
-
Have pointers to useful resources in digital library research.
Session Outline
-
Informatics Research Agenda for Digital Libraries
-
Basic Principles in the Design and Implementation of a Digital Library
-
System Design Principles and Practices
-
Standards
-
Modularity
-
Extensibility
-
New technologies
-
Content and Collection-based Principles and Practices
-
Data acquisition and selection
-
Metadata
-
Intellectual property
-
Permanence and persistence of digital objects
-
Human Factors Principles and Practices
-
Accessibility, usability
-
Automation of manual tasks
-
Case Study
-
Hands-on Exercise
Session 2: 10:30 AM - 12:00 N
Genomics
Faculty
Issac Kohane, M.D., Ph.D.
Educational Objectives
-
Learn how to interpret a the results of a functional genomics study written
in publication
-
Learn how to view the impact of genomics on individualized medicine
Session Outline
-
Why bioinformatics is central to the genomics revolution
-
Brief refesher on basic genomic biology
-
What is functional genomics and what are the principal bioinformatics techniques
used in elucidating the function of genes?
-
Shared themes in clinical informatics and bioinformatics; why these are
two sides of a single discipline.
Sessions 3 and 4: 1:30 -5:00 PM
Clinical Information Systems
Faculty
W. Edward
Hammond, Ph.D
Educational Objectives
Session Outline
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Day 6 - Saturday, June 1, 2002
Session 1: 8:30 - 10:00 AM
Education Informatics - Technology, Objectives, and the Learning Environment
Faculty
Christopher Cimino,
M.D.
Educational Objectives
This session will look at the application of technology to teaching health
care and the integration of medical informatics teaching in the educational
environment. At the completion of this session participants will
-
have an understanding of the basic building blocks of the educational interaction:
communication, assessment, role-modeling, skills development, and dialogue.
-
be exposed to an example of Medical Informatics objectives with a focus
on distinguishing skills, knowledge and attitudes.
-
understand how Informatics skills, knowledge, and attitudes relate to different
educational interactions; particularly role-modeling and skill development.
-
understand how specific Medical Informatics objectives relate to specfic
types of educational technology
-
be exposed to several types of educational technology and understand how
each complements or complicates each type of interaction
-
understand how Informatics teaching can be integrated with other medical
education.
Outline
-
How Does Education Occur?
-
How do we teach?
-
How do we choose what to teach?
-
What is the educational environment?
-
How does teaching occur?
-
Where does teaching occur?
-
What passes between teacher and student
-
Benefits of Integrated Education
-
Obstacles to Integrated Education
-
Where does technology fit in?
-
How do we decide what to teach?
-
Mission
-
Needs
-
Goals
-
Objectives
-
Solutions
-
How do we decide what to teach?
-
Knowledge Objectives
-
Skill Objectives
-
Attitude Objectives
-
IMIA Medical Informatics Objectives
-
Organizing principles
-
Domain topics
-
IT User vs. IT Specialist
-
Degree of career progression
-
Examples of teaching and assessing Informatics objectives
-
Skills
-
Knowledge
-
Attitude
-
Technology as a teaching tool
-
Infrastructure needed to teach skills
-
Role models needed for teaching attitude
-
Integration into work-flow needed to develop role models
-
How do we decide what to teach?
-
Student Evaluation
-
Program Evaluation
-
Evaluation of educational technology
-
Education success as measured by science
-
Cost
-
Satisfaction
-
Social Change
-
Changing the environment
-
What kind of institution are you at?
-
Your setting determines stakeholders
-
Stakeholders
-
Who determines educational approach?
-
Who determines educational content?
-
Who supports technology?
-
Instigating Change
-
Innovation
-
Long term growth
-
"Willing" but cautious participants
-
Implementing Change
-
Make use of power of iteration
-
Conserve support effort
-
Shape user expectations to be reasonable
-
Making use of early failure
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Session 2: 10:30 AM - 12:00
N
Education Informatics - Faculty Development
Faculty
Christopher Cimino,
M.D.
Educational Objectives
This session will look at the adaption of clinical faculty to teaching
medical informatics. Using specific examples on the internet, participants
will face and overcome some of the common obstacles. At the completion
of this session
participants will have
-
gained practical skills in finding informatics information geared to education.
-
understand the obstacles to motivating faculty to integrate informatics
teaching into other disciplines
-
know the types of behaviors that promote positive attitudes amoung collegues
and students
Session Outline
Each exercise will be followed by a group discussion of the results
of the exercise and concrete lessons learned.
Exercise 1:
Internet resources to enhance
the teaching of a skill objective
Examining learning curve
obstacles.
Exercise 2:
Internet resources to enhance
the teaching of a knowledge objective
Examining quality obstacles
Exercise 3:
Internet resources to enhance
the teaching of a attitude objective
Examining reliability obstacles
Other obstacles:
Social obstacles
Work flow obstacles
Resource obstacles
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Session 3: 1:30 - 3:00 PM
Designing a medical informatics curriculum
Faculty
Faculty Panel
Educational Objectives
At the completion of this session, participants should have an understanding
of issues attendant to the development and implementation of a medical
informatics curriculum at the fellows' home institutions.
Session Outline
This session will be an interactive discussion among faculty and fellows.
It will review the topics covered at the MBL course and promote discussion
regarding future changes.
3:00 PM
Course Wrap-Up and Farewell
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Last Updated: 13 May 2001
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